Crosslinking Reagents
Abcam Disuccinimidyl suberate, cross-linking reagent, 5G
MW 368.34 Da, Purity >99%. Homobifunctional primary amine reactive cross-linker. Contains an 8 atom linker (11.4 Å) and can cross-link distances up to ~25 Å due to protein flexibility. Produces no toxic side products.
The product is subject to the following: Abcam Restricted Use Statement
TARGETMOL CHEMICALS INC DSG CROSSLINKER 100MG
Also available in 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DSG Crosslinker is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. purity: 98%
Bioworld NHS LC SPDP , 100 mg
NHS LC SPDP, Succinimidyl 6-[3-(2-pyridylthio) propionamido] HexanoateSpacer arm SPDPAntibody-toxin conjugationReferences: 1.) Carlsson, J., et al. (1978) Biochem. J. 173, 723-737.M.W. = 425.5
Bioworld Sulfo-MPS, 50 mg
Sulfo MPS, Maleimidopropionic acid N-hydroxysulfosuccinimide esterSulfhydryl reactivePrimary amine reactiveWater solubleM.W. = 381.27
Bioworld Sulfo-EMCS, 50 mg
Sulfo EMCS, [N-(E-malemidocaproyloxy)-sulfosuccinimide]Primary amine reactiveSulfhydryl reactiveWater solubleReferences:Kitagawa, T., et al. (1981) Chem. Pharm. Bull. 29, 1130. 2.) Keller, O. and Rudinger, J., Helv. Chem. Acta, 58, 531.M.W. = 410.35
![eMolecules Medchem Express / UAA crosslinker 1 (hydrochloride) / 25mg / 705860188 / HY-111434A / / 1994331-17-7 / [null] / 295.720 / C9H18ClN5O4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502446706.PNG-250.jpg)
eMolecules Medchem Express / UAA crosslinker 1 (hydrochloride) / 25mg / 705860188 / HY-111434A / / 1994331-17-7 / [null] / 295.720 / C9H18ClN5O4
Medchem Express / UAA crosslinker 1 (hydrochloride) / 25mg / 705860188 / HY-111434A / / 1994331-17-7 / [null] / 295.720 / C9H18ClN5O4
Cayman Chemical N-Hydroxysulfosuccinimide so
A topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes molds yeasts dimorphic fungi and some Gram-positive bacteria a potent inhibitor of cytochrome P450 aromatase (Ki 68 nM IC50 270 nM)
Cayman Chemical 1 7-DImethylurIc AcId 50mg
A synthetic derivative of staurosporine that inhibits a variety of kinases including Akt protein kinase C (IC50 30 nM) PDK1 (IC50 6 nM) and cyclin-dependent kinases (IC50s 300-600 nM for Cdk1 and Cdk2) arrests tumor cells in the G1/S phase of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase Chk1 (IC50 7 nM) leading to apoptosis
Cayman Chemical DIsuccInImIdyl Glutarate 25mg
A dual inhibitor of EGFR and HER2 (IC50s 92 and 59 nM respectively) selective for EGFR and HER2 over a panel of 12 kinases (IC50s 5000 nM) but does inhibit VEGFR2 and Src (IC50s 800 and 1400 nM respectively) inhibits the proliferation of NCI H508 colorectal cancer cells expressing wild-type or mutant forms of HER2 (IC50s 0 2-3 nM) reduces tumor growth in BT474 breast and SKOV3 ovarian cancer mouse xenograft models at 40 mg/kg
Sigma Organic Chemistry SMCC CONJUGATION KIT FOR IRON OXIDE (II III) NANOPARTICLES 20 NM AMINE FUNCTIONALIZED 5 MG/ML | 1KT
SMCC CONJUGATION KIT FOR IRON OXIDE (II III) NANOPARTICLES 20 NM AMINE FUNCTIONALIZED 5 MG/ML, 1KT
About This Item:
UNSPSC Code: 12352302
Storage: COOLER/REFRIGERATED
Sigma Organic Chemistry EDC CONJUGAITON KIT FOR IRON OXIDE (II III) NANOPARTICLES 30 NM CARBOXYLIC ACID FUNCTIONALIZED 5 MG/ML | 1KT
EDC CONJUGAITON KIT FOR IRON OXIDE (II III) NANOPARTICLES 30 NM CARBOXYLIC ACID FUNCTIONALIZED 5 MG/ML, 1KT
About This Item:
UNSPSC Code: 12352302
Storage: COOLER/REFRIGERATED